BDBM50589206 CHEMBL5184084
SMILES CC(C)(\C=C(\C#N)C(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)N1CCOCC1
InChI Key InChIKey=NZIQNLGMMJGSQU-MUGAAPJKSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50589206
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of BTK (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of biotinylated-labeled BTK-selective probe binding to BTK in human Ramos assessed as target occupancy pretreated for 1 hr followed by pro...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of BLK (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of BMX (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of RLK (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 177nMAssay Description:Inhibition of ERBB4 (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of ITK (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of TEC (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Principia Biopharma, A Sanofi
Curated by ChEMBL
Principia Biopharma, A Sanofi
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of ERBB2 (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair