BDBM50594634 CHEMBL5182250

SMILES Nc1nc(Nc2ccco2)nc2sc(Cc3cccnc3)nc12

InChI Key InChIKey=JQEUVIGFWWXQIW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594634   

TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50594634(CHEMBL5182250)
Affinity DataIC50: 1.60nMAssay Description:Inverse agonist activity at human A2A receptor assessed as inhibition of basal cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50594634(CHEMBL5182250)
Affinity DataKi:  11nMAssay Description:Binding affinity to human adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50594634(CHEMBL5182250)
Affinity DataIC50: 36nMAssay Description:Inverse agonist activity at human A2A receptor assessed as inhibition of selective agonist-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed