BDBM50595734 CHEMBL5197209

SMILES CNc1nc(NCc2cccc(NC(=O)CCl)c2)nc(Nc2cc([nH]n2)C(C)(C)C)n1

InChI Key InChIKey=KBYGFCKQWFCORZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595734   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50595734(CHEMBL5197209)
Affinity DataIC50:  9nMAssay Description:Inhibition of JAK3 (unknown origin) using TK peptide as substrate incubated for 1 hr in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50595734(CHEMBL5197209)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of BTK (unknown origin) using TK peptide as substrate incubated for 1 hr in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed