BDBM50602407 CHEMBL5206532

SMILES ClCC(=O)N1CCN([C@@H](C1)C(=O)NCc1cccs1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=DBKURSLDNAKNLU-INIZCTEOSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50602407   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50602407(CHEMBL5206532)
Affinity DataIC50:  180nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50602407(CHEMBL5206532)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human cathepsin B using Z-Leu-Arg-AMC as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCaspase-3(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50602407(CHEMBL5206532)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human caspase 3 using Ac-Asp-Glu-Val-Asp-pNA as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin K(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50602407(CHEMBL5206532)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human cathepsin K using Ac-LR-AFC as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50602407(CHEMBL5206532)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human cathepsin L using Z-Leu-Arg-AMC as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin F(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50602407(CHEMBL5206532)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human cathepsin F using Z-Phe-Arg-AMC as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed