BDBM50652932 CHEMBL1738759

SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2ccc3c(c2)C[C@@H](C(=O)O)NC3)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50652932   

TargetTyrosine-protein kinase ABL1(Human)
Tufts Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652932BDBM50652932(CHEMBL1738759)
Affinity DataIC50: 57nMAssay Description:Inhibition of human N-terminal his tagged native ABL1 (229 to 499 residues) expressed in Sf9 cells using ABLtide as substrate preincubated for 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Tufts Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652932BDBM50652932(CHEMBL1738759)
Affinity DataIC50: 773nMAssay Description:Inhibition of human ABL1 T315I mutant (229 to 499 residues) using ABLtide as substrate preincubated for 2 hrs followed by ATP addition and measured e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed