BDBM5075 1,2,4-Oxadiazole Analogue 5n::4-[(2S)-2-{[(1S)-1-{3-[(3-bromo-4-iodophenyl)methyl]-1,2,4-oxadiazol-5-yl}ethyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid

SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)c1nc(Cc2ccc(I)c(Br)c2)no1

InChI Key InChIKey=SNNBVQCDFCRWJX-BUXKBTBVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5075   

TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5075(1,2,4-Oxadiazole Analogue 5n | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5075(1,2,4-Oxadiazole Analogue 5n | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM5075(1,2,4-Oxadiazole Analogue 5n | 4-[(2S)-2-{[(1S)-1-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed