BDBM510694 US11078186, Example 148

SMILES OC(c1ccc(cc1)[C@@H]1CN(C[C@H]1Cc1ccccc1)C(=O)Cc1ccc(cc1)C#N)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JUTBZVGFWFSWMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510694   

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510694(US11078186, Example 148)
Affinity DataIC50: 1.28E+3nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent