BDBM521005 (−)-Sodium 5-({[6-bromo-3-methyl-2-(pyrrolidin-1-yl)quinolin-4-yl]carbonyl}amino)-4-(2-chlorophenyl)pentanoate (Enantiomer 1)::US11149018, Example 285::US11149018, Example 288

SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)NC[C@H](CCC([O-])=O)c1ccccc1Cl)N1CCCC1

InChI Key InChIKey=YQOLEILXOBUDMU-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521005   

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 521005BDBM521005(US11149018, Example 288 | (−)-Sodium 5-({[6-...)
Affinity DataIC50: 5.30nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 521005BDBM521005(US11149018, Example 288 | (−)-Sodium 5-({[6-...)
Affinity DataIC50: 14nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent