BDBM542554 (R)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3- b]pyridin-6-yl)-2-methylbut-3-yn-2-amine::(S)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine::US11274108, Example 1-5-enant-B

SMILES CC(C)(C#Cc1cc2c(nc1)n(cn2)Cc3ccc4c(c3)OC[C@@H](O4)c5ccc(nc5)OC)N

InChI Key InChIKey=DRBFONOVLOXKJM-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542554   

LigandChemical structure of BindingDB Monomer ID 542554BDBM542554(US11274108, Example 1-5-enant-B | (S)-4-(3-((2-(6-...)
Affinity DataIC50: 16nMAssay Description:All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2022
Entry Details
US Patent