BDBM559773 Methyl (S)-2-((4-(2-((4-cyano-2-fluorobenzyl)oxy)pyrimidin-4-yl)piperidin-1-yl)methyl)-4-(1-methyl-1H-pyrazol-3-yl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylate::WO2022109182, Example 4

SMILES Cn1ccc(n1)-c1cc(cc2n(C[C@@H]3CCO3)c(CN3CCC(CC3)c3ccnc(OCc4ccc(cc4F)C#N)n3)nc12)C(O)=O

InChI Key InChIKey=MFYHDTJUQLZMCO-VWLOTQADSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559773   

TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559773(Methyl (S)-2-((4-(2-((4-cyano-2-fluorobenzyl)oxy)p...)
Affinity DataIC50:  1.20nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed