BDBM577739 US11478460, Compound 1.079

SMILES CCc1cccc(CC)c1-n1nc2CCN(Cc2c1-c1cc(F)c(NC(N)=O)cc1F)C(CO)c1ccccc1

InChI Key InChIKey=JNBQZBPUKCXUAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577739   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM577739(US11478460, Compound 1.079)
Affinity DataIC50: 27.5nMAssay Description:Optionally, compounds may be further assayed for their ability to inhibit chemotaxis in cells. Chemotaxis assays are performed using 5 μm pore p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent