BDBM60532 US9102591, 2-chloro-6-fluoro-N-[1-[4-2-methylpyrimidin-5-yl)tetrahydropyran-4-yl]ethyl]benzmide::US9649308, 2-chloro-6-fluoro-N-[1-[4-(2-methylpyrimidin-5-yl)tetrahydropyran-4-yl]ethyl]benzamide

SMILES CC(NC(=O)c1c(F)cccc1Cl)C1(CCOCC1)c1cnc(C)nc1

InChI Key InChIKey=MQWUFPQPJYHBKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 60532   

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM60532(US9102591, 2-chloro-6-fluoro-N-[1-[4-2-methylpyrim...)
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM60532(US9102591, 2-chloro-6-fluoro-N-[1-[4-2-methylpyrim...)
Affinity DataIC50: 55nMAssay Description:Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent