BDBM646597 N-[5-(2,2-difluoroethoxy)-4,6- dimethoxy-pyrimidin-2-yl]-6- (difluoromethyl)-1H-indole-3- sulfonamide::US20240025883, Example 102

SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(ccc23)C(F)F)nc(OC)c1OCC(F)F

InChI Key InChIKey=XDNLSEFACSDHDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646597   

TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM646597(N-[5-(2,2-difluoroethoxy)-4,6- dimethoxy-pyrimidin...)
Affinity DataIC50:  14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent