BDBM70884 US9546164, 57::US9694002, 57

SMILES Fc1cc(CN2CCC(CC2)Oc2cc(Cl)cc(Cl)c2)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1

InChI Key InChIKey=REXKPUWAXOQORC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 70884   

TargetSodium channel protein type 5 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM70884(US9694002, 57 | US9546164, 57)
Affinity DataIC50: 3.80nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
US Patent

LigandPNGBDBM70884(US9694002, 57 | US9546164, 57)
Affinity DataIC50: 3.80nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
US Patent