BDBM712376 US20250011330, Compound 10a

SMILES O=C(O)c1ccc(Nc2c(-c3ccccc3)nc3cnccn23)cc1C(=O)O

InChI Key InChIKey=DQITWSHGMZMNEP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712376   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM712376(US20250011330, Compound 10a)
Affinity DataIC50: 4.55E+4nMAssay Description:Table 1 and 2: TDP1 Gel-based in vitro assay was carried out as previously described Lountos, G. T., et al. (Nucleic Acids Res. (2019) 47(19) 10134-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent