BDBM74255 (3-amino-2-methyl-phenyl)amine::1,3-Benzenediamine, 2-methyl-::2-methylbenzene-1,3-diamine::MLS002174248::SMR001261423::cid_13205
SMILES Cc1c(N)cccc1N
InChI Key InChIKey=RLYCRLGLCUXUPO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 74255
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation using PIP2 as substrate after 45 mins by fluorescence po...More data for this Ligand-Target Pair
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair