BDBM82087 2-(5-methoxy-1H-indol-3-yl)ethanamine::5-MT::5-Methoxytryptamine hydrochloride::CAS_66-83-1::tryptamine, 5-Methoxy

SMILES COc1ccc2[nH]cc(CCN)c2c1

InChI Key InChIKey=JTEJPPKMYBDEMY-UHFFFAOYSA-N

Data  145 KI  2 IC50  4 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82087   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataKi:  4.80nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (D) labeled with [125I]-DOI.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataKi:  300nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (K) labeled with [3H]-ketanserin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataKi:  500nMAssay Description:Affinity against 5-hydroxytryptamine 2C receptor in J1 cells transfected with the rat 5-HT2C gene labeled with [3H]-mesulergine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed