BDBM9028 Indole-Tacrine Heterodimer 11::N-(3-{[3-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-propyl]methylamino}propyl)-3-(1H-indol-3-yl)propionamide::N-[3-({3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}(methyl)amino)propyl]-3-(1H-indol-3-yl)propanamide

SMILES CN(CCCNC(=O)CCc1c[nH]c2ccccc12)CCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=ZNDUXFVNQAAWFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9028   

TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9028(Indole-Tacrine Heterodimer 11 | N-(3-{[3-(6-Chloro...)
Affinity DataIC50:  2.90nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9028(Indole-Tacrine Heterodimer 11 | N-(3-{[3-(6-Chloro...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9028(Indole-Tacrine Heterodimer 11 | N-(3-{[3-(6-Chloro...)
Affinity DataIC50:  21.4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed