Compile Data Set for Download or QSAR
Report error Found 223 Enz. Inhib. hit(s) with Target = '7-dehydrocholesterol reductase'
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407454BDBM50407454(CHEMBL5281526)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20607BDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataKd:  1nMAssay Description:Binding affinity towards antiestrogen binding site AEBSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396754BDBM50396754(CHEMBL2172347)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406621BDBM50406621(CHEMBL9820)
Affinity DataKi:  4nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  5.5nMAssay Description:Binding affinity to human DHCR7 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229744BDBM229744(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(3-(trifluorom...)
Affinity DataKi:  6.87nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406617BDBM50406617(CHEMBL276388)
Affinity DataKi:  7nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229678BDBM229678((S)-4-((1R,3r,5S,6S)-6-(1- isopropyl-3-(2-(trifluo...)
Affinity DataKi:  7.22nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229766BDBM229766(4-((1R,3r,5S,6r)-6-(3-(2- fluorophenyl)-1-isopropy...)
Affinity DataKi:  7.29nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229746BDBM229746(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(4-(trifluorom...)
Affinity DataKi:  7.81nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229764BDBM229764(3-(5-((1R,3r,5S,6r)-3-(1,4- oxazepan-4-yl)bicyclo[...)
Affinity DataKi:  8.04nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229772BDBM229772(4-((1R,3r,5S,6r)-6-(3-(3- (difluoromethoxy)phenyl)...)
Affinity DataKi:  8.20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 227114BDBM227114(4-((1S,3R)-3-(1-isopropyl-3- (6-(trifluoromethyl)p...)
Affinity DataKi:  8.28nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229749BDBM229749(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(3-(trifluorom...)
Affinity DataKi:  8.64nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229649BDBM229649((R)-4-((1R,3r,5S,6S)-6-(1- isopropyl-3-(3-(trifluo...)
Affinity DataKi:  8.76nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229682BDBM229682(4-((1S,3R)-3-(1-isopropyl-3- (6-(trifluoromethyl)p...)
Affinity DataKi:  8.89nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 227127BDBM227127(4-((1R,3S)-3-(1-isopropyl-3- (3-(trifluoromethyl)p...)
Affinity DataKi:  8.90nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229762BDBM229762(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(3-(trifluorom...)
Affinity DataKi:  9.14nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229763BDBM229763(4-((1R,3s,5S,6r)-6-(1-iso- propyl-3-(3-(trifluorom...)
Affinity DataKi:  9.63nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229693BDBM229693(4-((1S,3R)-3-(3-(3-fluoro-4- (trifluoromethyl)phen...)
Affinity DataKi:  9.73nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229770BDBM229770(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(o-tolyl)-1H- ...)
Affinity DataKi:  9.87nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 227123BDBM227123(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(3-(trifluorom...)
Affinity DataKi:  9.93nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229754BDBM229754(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(4-(trifluorom...)
Affinity DataKi:  10.1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229756BDBM229756(4-((1R,3r,5S,6r)-6-(3-(4- fluorophenyl)-1-isopropy...)
Affinity DataKi:  10.6nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229636BDBM229636(4-((1R,3r,5S,6r)-6-(1-ethyl- 3-(5-(trifluoromethyl...)
Affinity DataKi:  10.6nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229659BDBM229659(1-((1S,3R)-3-(1-isopropyl-3- (6-(trifluoromethyl)p...)
Affinity DataKi:  10.9nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229752BDBM229752(4-(5-((1R,3r,5S,6r)-3-(1,4- oxazepan-4-yl)bicyclo[...)
Affinity DataKi:  10.9nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 227125BDBM227125(4-((1S,3R)-3-(1-isopropyl-3- (3-(trifluoromethyl)p...)
Affinity DataKi:  10.9nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229774BDBM229774(4-((1R,3r,5S,6r)-6-(3-(4- (difluoromethoxy)phenyl)...)
Affinity DataKi:  11nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229677BDBM229677((S)-4-((1R,3s,5S,6S)-6-(1- isopropyl-3-(2-(trifluo...)
Affinity DataKi:  11nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229666BDBM229666(1-((1R,3R)-3-(1-isopropyl-3- (6-(trifluoromethyl)p...)
Affinity DataKi:  11nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229718BDBM229718((R)-2-ethyl-4-((1R,3S)-3-(3- (5-fluoro-6-(trifluor...)
Affinity DataKi:  11.3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229773BDBM229773(4-((1R,3s,5S,6r)-6-(3-(3- (difluoromethoxy)phenyl)...)
Affinity DataKi:  11.6nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229675BDBM229675(4-((1R,3s,5S,6r)-6-(1-iso- propyl-3-(2-(trifluorom...)
Affinity DataKi:  11.7nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229686BDBM229686(4-((1R,3s,5S,6r)-6-(1-iso- propyl-3-(6-(trifluorom...)
Affinity DataKi:  11.7nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229758BDBM229758(4-((1R,3r,5S,6r)-6-(1- isopropyl-3-(4-(trifluoro- ...)
Affinity DataKi:  12nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Rat)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406618BDBM50406618(CHEMBL9875)
Affinity DataKi:  12nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229654BDBM229654(4-((1R,3r,5S,6r)-6-(3-(3- (difluoromethoxy)phenyl)...)
Affinity DataKi:  12nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229733BDBM229733(4-((1S,3S)-3-(3-(6-fluoro-5- (trifluoromethyl)pyri...)
Affinity DataKi:  12.2nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229594BDBM229594(4-((1R,3s,5S,6r)-6-(1-ethyl- 3-(5-(trifluoromethyl...)
Affinity DataKi:  12.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229765BDBM229765(3-(5-((1R,3s,5S,6r)-3-(1,4- oxazepan-4-yl)bicyclo[...)
Affinity DataKi:  12.6nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229768BDBM229768(4-((1R,3r,5S,6r)-6-(3-(3- fluorophenyl)-1-isopropy...)
Affinity DataKi:  12.7nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229769BDBM229769(4-((1R,3s,5S,6r)-6-(3-(3- fluorophenyl)-1-isopropy...)
Affinity DataKi:  12.7nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229667BDBM229667(1-((1S,3R)-3-(1-isopropyl-3- (6-(trifluoromethyl)p...)
Affinity DataKi:  12.8nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229641BDBM229641(4-((1S,3S)-3-(1-isopropyl-3- (5-(trifluoromethyl)p...)
Affinity DataKi:  13.1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229767BDBM229767(4-((1R,3s,5S,6r)-6-(3-(2- fluorophenyl)-1-isopropy...)
Affinity DataKi:  13.1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229745BDBM229745(4-((1R,3r,5S,6r)-6-(1-iso- propyl-3-(2-(trifluorom...)
Affinity DataKi:  13.4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  14nMAssay Description:Binding affinity to human DHCR7 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229748BDBM229748(4-((1R,3s,5S,6r)-6-(1-iso- propyl-3-(3-(trifluorom...)
Affinity DataKi:  14.2nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

Target7-dehydrocholesterol reductase(Human)
Gitam (Deemed To Be University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 229642BDBM229642(4-((1R,3R)-3-(1-isopropyl-3- (5-(trifluoromethyl)p...)
Affinity DataKi:  14.4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent

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