Compile Data Set for Download or QSAR
Report error Found 649 Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family C member 4'
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50172903(3,4-diarylpyrazoline derivative | CHEMBL364300)
Affinity DataKi:  7.00E+3nMAssay Description:Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  4.00E+3nMAssay Description:Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50420252(CHEMBL2074587)
Affinity DataIC50: 4.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50375594(TAUROCHOLATE)
Affinity DataIC50: 3.50E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50375594(TAUROCHOLATE)
Affinity DataIC50: 2.50E+5nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM81199((Z)-but-2-enedioate;ethyl N-[2-azanyl-6-[(4-fluoro...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50031459((2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcycloh...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50247882(CHEBI:32260 | Modrastane | Modrenal | Trilostane |...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50139772(leurocristine | 22-oxovincaleukoblastine | vincris...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM12578(CHEMBL924 | [1-hydroxy-2-(1H-imidazol-1-yl)-1-phos...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50103599(CHEBI:50694 | Minocycline)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50247884(Hidrasec | Racecadotril)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50237618(CHEBI:35455 | 1-Naphthyl Isothiocyanate | 1-Naphth...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50017666(2-(p-bromo-alpha-(2-dimethylaminoethyl)benzyl)pyri...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50237610(CHEBI:27385 | Carbon Tetrachloride)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM31915(HPMPC | Vistide | CDV | Cidofovir | US10071110, Co...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50017674(Hydramine | Benylin | Silphen | (2-Benzhydryloxy-e...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50302225(escitalopram | (1S)-1-[3-(dimethylamino)propyl]-1-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50247892(CHEBI:31810 | AM-833 | Fleroxacin | Megalone | Ro-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50017811(CHEMBL467 | US10155732, Compound HU | HU | hydroxy...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM10850(1-(5-Oxohexyl)theobromine (pentoxifylline) | 3,7-d...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50164279(CHEMBL1059 | (S)-3-Aminomethyl-5-methyl-hexanoic a...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50118470(CHEMBL1218 | N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50247904(CHEBI:75176 | Ornidazole | Ro-70207 | Tiberal)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50237606(CHEMBL521606)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50247908(CHEBI:31905 | Ikorel | Nicorandil | SG-75)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50028197(2-(difluoromethyl)ornithine | CHEMBL830 | EFLORNIT...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50054601(5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50103518(CHEBI:2453 | Aciclovir | Acycloguanosine | Acyclov...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50048280(6-(3-adamantan-1-yl-4-methoxyphenyl)naphthalene-2-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM25764(ALPRENOLOL,(-) | CHEMBL266195 | ALPRENOLOL,(+) | A...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50237603(CHEBI:2637 | Amikacin | Amikin)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM81790(NSC_2159 | CAS_71675-85-9 | Amisulpride | US101672...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50088383(CHEBI:2668 | Amlodipine | Norvasc)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM22870(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50350464(Amoxi-Inject | Amoxi-Tabs | Amoxicillin | AMOXICIL...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM10015(NSC719344 | arimidex | 2-[3-(1-cyano-1-methylethyl...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
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