Compile Data Set for Download or QSAR
Report error Found 658 Enz. Inhib. hit(s) with Target = 'Asialoglycoprotein receptor 1'
TargetAsialoglycoprotein receptor 1(Rat)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 660609BDBM660609(US20240092819, Compound 262)
Affinity DataIC50: 48nMAssay Description:The assay was performed in 384-well microplates (GREINER bio-one, 781076). Membrane prepared from Wistar rat liver was used as a source of ASGPR and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Rat)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 660608BDBM660608(US20240092819, Compound 261)
Affinity DataIC50: 58nMAssay Description:The assay was performed in 384-well microplates (GREINER bio-one, 781076). Membrane prepared from Wistar rat liver was used as a source of ASGPR and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Mouse)
Leiden University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074090BDBM50074090(Galactoside analogue | CHEMBL2368210)
Affinity DataKi:  93nMAssay Description:Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAsialoglycoprotein receptor 1(Mouse)
Leiden University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074091BDBM50074091(Galactoside analogue | CHEMBL2368208)
Affinity DataKi:  93nMAssay Description:Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAsialoglycoprotein receptor 1(Mouse)
Leiden University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074089BDBM50074089(TG(20)C-Galactoside analogue | CHEMBL2368207)
Affinity DataKi:  200nMAssay Description:Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAsialoglycoprotein receptor 1(Rat)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 660614BDBM660614(US20240092819, Compound 268)
Affinity DataIC50: 335nMAssay Description:The assay was performed in 384-well microplates (GREINER bio-one, 781076). Membrane prepared from Wistar rat liver was used as a source of ASGPR and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Rat)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 660613BDBM660613(US20240092819, Compound 267)
Affinity DataIC50: 563nMAssay Description:The assay was performed in 384-well microplates (GREINER bio-one, 781076). Membrane prepared from Wistar rat liver was used as a source of ASGPR and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Rat)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 660615BDBM660615(US20240092819, Compound 269)
Affinity DataIC50: 598nMAssay Description:The assay was performed in 384-well microplates (GREINER bio-one, 781076). Membrane prepared from Wistar rat liver was used as a source of ASGPR and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408867BDBM408867(US10376531, Compound 27 | US10813942, Compound 27)
Affinity DataKd:  700nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408867BDBM408867(US10376531, Compound 27 | US10813942, Compound 27)
Affinity DataKd:  1.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408863BDBM408863(US10376531, Compound 24 | US10813942, Compound 24)
Affinity DataKd:  1.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408868BDBM408868(US10376531, Compound 28 | US10813942, Compound 28)
Affinity DataKd:  1.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408863BDBM408863(US10376531, Compound 24 | US10813942, Compound 24)
Affinity DataKd:  1.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Rat)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 660610BDBM660610(US20240092819, Compound 263)
Affinity DataIC50: 1.64E+3nMAssay Description:The assay was performed in 384-well microplates (GREINER bio-one, 781076). Membrane prepared from Wistar rat liver was used as a source of ASGPR and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408868BDBM408868(US10376531, Compound 28 | US10813942, Compound 28)
Affinity DataKd:  2.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408858BDBM408858(US10376531, Compound 20 | US10813942, Compound 20)
Affinity DataKd:  2.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408862BDBM408862(US10376531, Compound 25 | US10813942, Compound 25)
Affinity DataKd:  2.20E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408860BDBM408860(US10376531, Compound 21 | US10813942, Compound 21)
Affinity DataKd:  2.60E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408856BDBM408856(US10376531, Compound 18 | US10813942, Compound 18)
Affinity DataKd:  3.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408862BDBM408862(US10376531, Compound 25 | US10813942, Compound 25)
Affinity DataKd:  3.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408856BDBM408856(US10376531, Compound 18 | US10813942, Compound 18)
Affinity DataKd:  3.10E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408859BDBM408859(US10376531, Compound 19 | US10813942, Compound 19)
Affinity DataKd:  3.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408860BDBM408860(US10376531, Compound 21 | US10813942, Compound 21)
Affinity DataKd:  3.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408858BDBM408858(US10376531, Compound 20 | US10813942, Compound 20)
Affinity DataKd:  3.40E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408857BDBM408857(US10376531, Compound 17 | US10813942, Compound 17)
Affinity DataKd:  3.80E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408859BDBM408859(US10376531, Compound 19 | US10813942, Compound 19)
Affinity DataKd:  4.70E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408857BDBM408857(US10376531, Compound 17 | US10813942, Compound 17)
Affinity DataKd:  5.30E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408861BDBM408861(US10376531, Compound 22 | US10813942, Compound 22)
Affinity DataKd:  5.50E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408861BDBM408861(US10376531, Compound 22 | US10813942, Compound 22)
Affinity DataKd:  6.50E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408865BDBM408865(US10376531, Compound 29 | US10813942, Compound 29)
Affinity DataKd:  6.90E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408853BDBM408853(US10376531, Compound 3 | US10813942, Compound 3)
Affinity DataKd:  7.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408853BDBM408853(US10376531, Compound 3 | US10813942, Compound 3)
Affinity DataKd:  7.18E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408855BDBM408855(US10376531, Compound 1 | US10813942, Compound 1)
Affinity DataKd:  9.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 408855BDBM408855(US10376531, Compound 1 | US10813942, Compound 1)
Affinity DataKd:  9.00E+3nMAssay Description:All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800049BDBM800049(US20260083851, Compound A342)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800050BDBM800050(US20260083851, Compound A343)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800051BDBM800051(US20260083851, Compound A344)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800052BDBM800052(US20260083851, Compound A345)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800053BDBM800053(US20260083851, Compound A346)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800054BDBM800054(US20260083851, Compound A351)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800055BDBM800055(US20260083851, Compound A352)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800056BDBM800056(US20260083851, Compound A353)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800041BDBM800041(US20260083851, Compound A334)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800042BDBM800042(US20260083851, Compound A335)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800043BDBM800043(US20260083851, Compound A336)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800044BDBM800044(US20260083851, Compound A337)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800045BDBM800045(US20260083851, Compound A338)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800046BDBM800046(US20260083851, Compound A339)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800047BDBM800047(US20260083851, Compound A340)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetAsialoglycoprotein receptor 1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 800048BDBM800048(US20260083851, Compound A341)
Affinity DataKd: <1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

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