Compile Data Set for Download or QSAR
Report error Found 498 Enz. Inhib. hit(s) with Target = 'C3a anaphylatoxin chemotactic receptor'
LigandPNGBDBM50520313(CHEMBL4519060)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520313(CHEMBL4519060)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520322(CHEMBL4556174)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520322(CHEMBL4556174)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50411335(CHEMBL228846)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human C3a receptor expressed on HMC1 cells by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50423086(CHEMBL243048)
Affinity DataIC50: 7.94E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50423069(CHEMBL233029)
Affinity DataIC50: 6.31E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50422997(CHEMBL228900)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human C3a receptor expressed on HMC1 cells by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50423083(CHEMBL234729)
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50105663(5,6-Dichloro-1,3-bis-[(Z)-2-p-tolyl-ethylimino]-2,...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50105664(N-{3-[(E)-4-Methyl-benzylimino]-1-[(Z)-4-methyl-be...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50322616((S)-2-((S)-1-((S)-2-((S)-1-((S)-2-amino-3-(1H-indo...)
Affinity DataIC50: 2.70E+4nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50322616((S)-2-((S)-1-((S)-2-((S)-1-((S)-2-amino-3-(1H-indo...)
Affinity DataIC50: 2.70E+4nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50423099(CHEMBL233232)
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50423090(CHEMBL232418)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50028776(CHEMBL3342682)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
LigandPNGBDBM50028776(CHEMBL3342682)
Affinity DataIC50: 1.90E+4nMAssay Description:Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
LigandPNGBDBM50423095(CHEMBL234521)
Affinity DataIC50: 1.58E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50105665(1,3-Bis-[(Z)-2-(4-fluoro-phenyl)-ethylimino]-2,3-d...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50423082(CHEMBL234731)
Affinity DataIC50: 1.26E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50423073(CHEMBL395233)
Affinity DataIC50: 1.26E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50105658(5-Methoxy-1,3-bis-[(Z)-2-p-tolyl-ethylimino]-2,3-d...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50105654(1,3-Bis-[(Z)-2-(4-fluoro-phenyl)-ethylimino]-2,3-d...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50520300(CHEMBL4439168)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520311(CHEMBL4521007)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520300(CHEMBL4439168)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520311(CHEMBL4521007)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50423078(CHEMBL234730)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50389003(CHEMBL2064018)
Affinity DataIC50: 8.91E+3nMAssay Description:Antagonist activity at C3a receptor in dbcAMP differentiated human U937 cells assessed as inhibition of increase in intracellular calcium compound pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50105656(1-[(Z)-2-(4-Chloro-phenyl)-ethylimino]-3-[(Z)-isop...)
Affinity DataIC50: 8.45E+3nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50322654((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...)
Affinity DataIC50: 7.94E+3nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50322654((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...)
Affinity DataIC50: 7.94E+3nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50105666(1,3-Bis-[(Z)-2-(3-chloro-phenyl)-ethylimino]-2,3-d...)
Affinity DataIC50: 7.48E+3nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50105657(1,3-Bis-[(Z)-2-(4-chloro-phenyl)-ethylimino]-2,3-d...)
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50520314(CHEMBL4472490)
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50423005(CHEMBL390834)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human C3a receptor expressed on HMC1 cells by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50028699(CHEMBL3342677)
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
LigandPNGBDBM50322651((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...)
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50322651((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...)
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50028699(CHEMBL3342677)
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
LigandPNGBDBM50105659(1,3-Bis-[(Z)-2-p-tolyl-ethylimino]-2,3-dihydro-1H-...)
Affinity DataIC50: 6.14E+3nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50520314(CHEMBL4472490)
Affinity DataIC50: 6.10E+3nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50105655(1,3-Bis-[(Z)-2-(4-fluoro-phenyl)-ethylimino]-5-pro...)
Affinity DataIC50: 5.97E+3nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50105660(1,3-Bis-[(Z)-2-(4-chloro-phenyl)-propylimino]-2,3-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50322623((2S,5S,8S,14S,17S)-17-amino-2-(3-guanidinopropyl)-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50322623((2S,5S,8S,14S,17S)-17-amino-2-(3-guanidinopropyl)-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
LigandPNGBDBM50105661(5-(2-Dimethylamino-ethoxy)-1,3-bis-[(Z)-2-(4-fluor...)
Affinity DataIC50: 5.36E+3nMAssay Description:Inhibition of complement component 3a (C3a) binding to C3a receptor in human neutrophil based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50423085(CHEMBL390036 | CHEMBL535624 | CHEMBL535625)
Affinity DataIC50: 5.01E+3nMAssay Description:Displacement of [125I]C3a from human C3a receptor expressed in HMC1 cells co-expressing aequorinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50520319(CHEMBL4572633)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50520319(CHEMBL4572633)
Affinity DataIC50: 3.98E+3nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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