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4F63:
Crystal structure of Human Fibroblast Growth Factor Receptor 1 Kinase domain in complex with compound 1
PDB ID:
4F63
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MMDB ID:
100406
PDB Deposition Date:
2012/5/14
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.55 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 4F63: dimeric; determined by author
Molecular Components in 4F63
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Fibroblast Growth Factor Receptor 1
(Gene symbol:
FGFR1
)
Chemicals and Non-standard biopolymers (6 molecules)
1
2
5-bromo-N~4~-(3-methyl-1H-pyrazol-5-yl)-N~2~-[2-(pyridin-3-yl)ethyl]pyrimidine-2,4-diamine
2
4
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303