1UK0: Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor

PDB ID: 1UK0Download
MMDB ID: 26260
PDB Deposition Date: 2003/8/13
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 1UK0: monomeric; determined by author
Molecular Components in 1UK0
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase-1
(Gene symbol: PARP1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303