2VC2: Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist L-739758

PDB ID: 2VC2Download
MMDB ID: 66409
PDB Deposition Date: 2007/9/18
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 2VC2: tetrameric; determined by author and by software (PISA)
Molecular Components in 2VC2
Label Count Molecule
Proteins (4 molecules)
1
Integrin Alpha-iib
Molecule annotation
1
Integrin Beta-3
Molecule annotation
1
Monoclonal Antibody 10e5 Heavy Chain
Molecule annotation
1
Monoclonal Antibody 10e5 Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
7
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
8
alpha-D-mannopyranosealpha-D-mannopyranose
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
GLYCEROLGLYCEROL
5
6
CALCIUM IONCALCIUM ION
6
1
2-(S)-[N-(3-PYRIDYLSULFONYL)AMINO]-3-[[2-CARBONYL-5-[2-(PIPERIDIN-4-YL)ETHYL]-THIENO[2,3-B]THIOPHENEYL]AMINO]-PROPIONIC ACID2-(S)-[N-(3-PYRIDYLSULFONYL)AMINO]-3-[[2-CARBONYL-5-[2-(PIPERIDIN-4-YL)ETHYL]-THIENO[2,3-B]THIOPHENEYL]AMINO]-PROPIONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303