3E63: Fragment Based Discovery Of Jak-2 Inhibitors

PDB ID: 3E63Download
MMDB ID: 67341
PDB Deposition Date: 2008/8/14
Updated in MMDB: 2008/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3E63: monomeric; determined by author and by software (PISA)
Molecular Components in 3E63
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Jak2
(Gene symbol: JAK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-phenyl-1h-indazol-3-amine5-phenyl-1h-indazol-3-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303