4DCH: Insights into Glucokinase Activation Mechanism: Observation of Multiple Distinct Protein Conformations

PDB ID: 4DCHDownload
MMDB ID: 97157
PDB Deposition Date: 2012/1/17
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.79  Å
Source Organism:
Similar Structures:
Biological Unit for 4DCH: monomeric; determined by author and by software (PISA)
Molecular Components in 4DCH
Label Count Molecule
Protein (1 molecule)
1
Glucokinase
(Gene symbol: GCK)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
(2R)-3-cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide(2R)-3-cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide
3
2
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303