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3TYV:
SAR development and discovery of potent indole-based inhibitors of the hepatitis C virus NS5B polymerase
PDB ID:
3TYV
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MMDB ID:
96915
PDB Deposition Date:
2011/9/26
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
1.65 Å
Source Organism:
Hepatitis C virus isolate HC-J4
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3TYV: monomeric; determined by author and by software (PISA)
Molecular Components in 3TYV
Label
Count
Molecule
Protein (1 molecule)
A
1
RNA-directed RNA Polymerase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PHOSPHATE ION
2
1
N-(cyclopropylsulfonyl)-1-(2,5-difluorobenzyl)-6-fluoro-5-methyl-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303