1ZQ5: Crystal structure of human androgenic 17beta-hydroxysteroid dehydrogenase type 5 in complexed with a potent inhibitor EM1404

PDB ID: 1ZQ5Download
MMDB ID: 234601
PDB Deposition Date: 2005/5/18
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.3  Å
Source Organism:
Similar Structures:
Biological Unit for 1ZQ5: monomeric; determined by author
Molecular Components in 1ZQ5
Label Count Molecule
Protein (1 molecule)
1
Aldo-keto Reductase Family 1 Member C3
(Gene symbol: AKR1C3)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ACETATE IONACETATE ION
2
1
3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN
3
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303