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4ERF:
crystal structure of MDM2 (17-111) in complex with compound 29 (AM-8553)
PDB ID:
4ERF
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MMDB ID:
99960
PDB Deposition Date:
2012/4/20
Updated in MMDB:
2012/05
Experimental Method:
x-ray diffraction
Resolution:
2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 4ERF: monomeric; determined by author and by software (PISA)
Molecular Components in 4ERF
Label
Count
Molecule
Protein (1 molecule)
A
1
E3 Ubiquitin-protein Ligase Mdm2
(Gene symbol:
MDM2
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
{(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl}acetic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303