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4ANW:
Complexes of PI3Kgamma with isoform selective inhibitors
PDB ID:
4ANW
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MMDB ID:
99406
PDB Deposition Date:
2012/3/22
Updated in MMDB:
2012/06
Experimental Method:
x-ray diffraction
Resolution:
2.31 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4ANW: monomeric; determined by author and by software (PISA)
Molecular Components in 4ANW
Label
Count
Molecule
Protein (1 molecule)
A
1
Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Gamma Isoform
(Gene symbol:
PIK3CG
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
SULFATE ION
2
1
3-AMINO-6-{4-CHLORO-3-[(2,3-DIFLUOROPHENYL)SULFAMOYL]PHENYL}-N-METHYLPYRAZINE-2-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303