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3ZC6:
Crystal Structure Of Jak3 Kinase Domain In Complex With An Indazole Substituted Pyrrolopyrazine Inhibitor
PDB ID:
3ZC6
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MMDB ID:
113668
PDB Deposition Date:
2012/11/16
Updated in MMDB:
2013/09
Experimental Method:
x-ray diffraction
Resolution:
2.42 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3ZC6: monomeric; determined by author and by software (PISA)
Molecular Components in 3ZC6
Label
Count
Molecule
Protein (1 molecule)
A
1
Tyrosine-protein Kinase Jak3
(Gene symbol:
JAK3
)
Chemicals and Non-standard biopolymers (5 molecules)
1
1
N-[(2r)-1-(3-Cyanoazetidin-1-Yl)-1-Oxidanylidene-Propan-2-Yl]-2-(6-Fluoranyl-1-Methyl-Indazol-3-Yl)-5h-Pyrrolo[2,3-B]pyrazine-7-Carboxamide
2
1
Di(Hydroxyethyl)ether
3
3
Chloride Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303