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• 4AN2: crystal structures of human mek1 with carboxamide-based allosteric inhibitor xl518 (gdc-0973), or related analogs. (10.1021/ML300049D )
• 4LMN: crystal structure of mek1 kinase bound to gdc0973 (10.1038/NATURE12441 )
• 7JUY: crystal structure of ksr1:mek1 in complex with amp-pnp, and allosteric mek inhibitor cobimetinib (10.1038/S41586-020-2760-4 )
• 7M0V: crystal structure of the braf:mek1 kinases in complex with amppnp and cobimetinib (10.1073/PNAS.2107207118 )