TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
H�Pital Kirchberg
Curated by ChEMBL
H�Pital Kirchberg
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transferMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of HIV-1 integrase-mediated 3'-processingMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibitory concentration against HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of HIV -1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of HIV -1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against 3'-processing of DNA by HIV-1 integraseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of HIV -1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processing methodMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-2 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-2 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibitory activity against HIV-1 Protease.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processing methodMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against purified recombinant integrase by strand transfer in vitro assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of HIV-1 integrase-mediated strand transferMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of HIV-1 integrase-mediated 3'-processingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against HIV-2 Integrase was measured using 3'-processing (3'-proc) assay.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of of HIV-2 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against purified recombinant integrase by 3'-processing in vitro assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against 3'-processing of DNA by HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against purified recombinant integrase by strand transfer in vitro assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HIV -1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration of compound against 3' processing of HIV-2 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV- integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against HIV-1 Protease.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 2More data for this Ligand-Target Pair