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Found 42 with Last Name = 'patil' and Initial = 'ad'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin K(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260286(CHEMBL508746 | cycloaltilisin 6)
Affinity DataIC50:  98nMAssay Description:Inhibition of cathepsin K (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029987(12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-di...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029982(12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-di...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase mutant (Tyr-181 to Cys)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029982(12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-di...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase mutant (Tyr-181 to Cys)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260285(1-(2,4-dihydroxyphenyl)-3-(2-(3,7-dimethylocta-2,6...)
Affinity DataIC50:  170nMAssay Description:Inhibition of cathepsin K (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029982(12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-di...)
Affinity DataIC50:  410nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase mutant (Tyr-181 to Leu)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292398((E)-5-octadecen-7,9-diynoic acid | CHEMBL489540)
Affinity DataIC50:  500nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50279762((5S)-9-chloro-5-methyl-6-(3-methylbut-2-enyl)-4,5,...)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029996(Acetic acid 2,3,10,10-tetramethyl-6-oxo-8-phenyl-3...)
Affinity DataIC50:  720nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260287(CHEMBL494579 | cycloaltilisin 7)
Affinity DataIC50:  840nMAssay Description:Inhibition of cathepsin K (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292397((Z)-5-octadecen-7,9-diynoic acid | CHEMBL504781)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292402((E)-octadecan-9-ynoic acid | CHEMBL482803)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292396((Z)-7-octedecan-9-ynoic acid | CHEMBL482601)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292399(7,9-tetradecadiynoic acid | CHEMBL501307)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292401(9-octadecynoic acid | CHEMBL482804 | Delta(9)-octa...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292404(3-(1,3 dodecadiynyl)-6-oxiranebutanoic acid | CHEM...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292400(7,9-octadecadiynoic acid | CHEMBL485858)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMacrophage scavenger receptor types I and II(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292390(CHEMBL454185 | Rigidone)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of full-length MSR1 transfected in HEK293 cells by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478563(CHEMBL450380)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478568(CHEMBL478973)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292403(6-hydroxy-7,9-octadecadiynoic acid | CHEMBL448462)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478565(CHEMBL476874)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029985(6,6,10,11-Tetramethyl-4-phenyl-6H,10H-dipyrano[2,3...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029988(6,6,10,11-Tetramethyl-4-phenyl-10,11-dihydro-6H-di...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478567(CHEMBL476873)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478566(CHEMBL478974)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029992(12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-di...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50478564(CHEMBL449762)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of HIV1 protease-mediated proteolysis of rabbit muscle lactate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of cathepsin K (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260288(CHEMBL495256 | Haploscleridamine)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of cathepsin K (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029981(12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-di...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029986(12-(4-Bromo-benzoyl)-6,6,10,11-tetramethyl-4-pheny...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029994(4-hydroxy-2,3,10,10-tetramethyl-8-phenyl-(2R,3S,4S...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage scavenger receptor types I and II(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292391((S)-1-methyl-4-(6-methylhept-5-en-2-yl)phenazine-2...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of full-length MSR1 transfected in HEK293 cells by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029990(3-(5-Hydroxy-2,3,8,8-tetramethyl-4-oxo-3,4-dihydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029991(Acetic acid 2,3,10,10-tetramethyl-6-oxo-8-phenyl-3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029995(6,6,10,11-Tetramethyl-4-phenyl-10,11-dihydro-6H-di...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029993(3-(5-Hydroxy-2,3,8,8-tetramethyl-4-oxo-3,4-dihydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029983(3-[7-Hydroxy-5-methoxy-2,2-dimethyl-6-(2-methyl-bu...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Smithkline Beecham Pharmaceuticals R&D

Curated by ChEMBL
LigandPNGBDBM50029984(4-hydroxy-2,3,10,10-tetramethyl-8-phenyl-(2R,3S,4S...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed