TargetDihydrofolate reductase(Homo sapiens (Human))
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Affinity DataKi: 10.2nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Affinity DataKi: 30.8nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program
Curated by ChEMBL
Affinity DataKi: 55.6nMAssay Description:Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 375nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
Affinity DataKi: 3.74E+3nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
Affinity DataKi: 3.92E+4nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at endothelin A receptor in rat A7r5 cells assessed as inhibition of ET-1-induced increase in cytosolic free Ca2+ level treated 1...More data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of TASK-3 (unknown origin) expressed in HEK293 cells by QPatch assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
University Of Kansas Specialized Chemistry Center
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human Haspin kinase domain using histone H3 biotin peptide as substrate preincubated with enzyme for 30 mins followed by substrate and ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair