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Found 63 with Last Name = 'difrancesco' and Initial = 'br'
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442766(CHEMBL2443358)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442776(CHEMBL2443348)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360383(CHEMBL1933700)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360381(CHEMBL1933694)
Affinity DataKi:  60nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442767(CHEMBL2443357)
Affinity DataKi:  70nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360382(CHEMBL1933699)
Affinity DataKi:  80nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442777(CHEMBL2443365)
Affinity DataKi:  80nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442770(CHEMBL2443354)
Affinity DataKi:  90nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360380(CHEMBL1933693)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442771(CHEMBL2443353)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442775(CHEMBL2443349)
Affinity DataKi:  111nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442764(CHEMBL2443360)
Affinity DataKi:  130nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442768(CHEMBL2443356)
Affinity DataKi:  160nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442773(CHEMBL2443351)
Affinity DataKi:  170nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442765(CHEMBL2443359)
Affinity DataKi:  200nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442769(CHEMBL2443355)
Affinity DataKi:  237nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360384(CHEMBL1933701)
Affinity DataKi:  250nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442774(CHEMBL2443350)
Affinity DataKi:  330nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442762(CHEMBL2443362)
Affinity DataKi:  350nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataKi:  398nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442761(CHEMBL2443364)
Affinity DataKi:  647nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360378(CHEMBL1933690)
Affinity DataKi:  790nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442772(CHEMBL2443352)
Affinity DataKi:  820nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50442763(CHEMBL2443361)
Affinity DataKi:  841nMAssay Description:Inhibition of recombinant human aromatase using O-dibenzylfluorescein benzyl ester as substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360379(CHEMBL1933692)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466399(CHEMBL4293388)
Affinity DataKi:  2.90E+3nMAssay Description:Partial mixed inhibition of Streptococcus pneumoniae apo-Pgda using N,N',N\"-triacetyl chitotriose as substrate in presence of ZnCl2 by fluorescamine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360379(CHEMBL1933692)
Affinity DataKi:  5.37E+3nMAssay Description:Inhibition of CYP1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360380(CHEMBL1933693)
Affinity DataKi:  3.09E+4nMAssay Description:Inhibition of CYP1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466409(CHEMBL4286586)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of His6-tagged Streptococcus pneumoniae Pgda C-terminal de-N-acetylase domain (232 to 431 residues) expressed in Escherichia coli BL21 (DE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466403(CHEMBL4292978)
Affinity DataKi:  5.80E+5nMAssay Description:Inhibition of His6-tagged Streptococcus pneumoniae Pgda C-terminal de-N-acetylase domain (232 to 431 residues) expressed in Escherichia coli BL21 (DE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360383(CHEMBL1933700)
Affinity DataKi:  7.08E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50360378(CHEMBL1933690)
Affinity DataKi:  1.12E+6nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466399(CHEMBL4293388)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466399(CHEMBL4293388)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466402(CHEMBL4291068)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466399(CHEMBL4293388)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466402(CHEMBL4291068)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466402(CHEMBL4291068)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466399(CHEMBL4293388)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466402(CHEMBL4291068)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466410(CHEMBL4294745)
Affinity DataIC50:  1.10E+6nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466404(CHEMBL4282480)
Affinity DataIC50:  4.90E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466405(CHEMBL4289694)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using acetoxy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466398(CHEMBL4279006)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466406(CHEMBL4283218)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using acetoxy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466410(CHEMBL4294745)
Affinity DataIC50:  5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466405(CHEMBL4289694)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466406(CHEMBL4283218)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase(Escherichia coli (Enterobacteria))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50466398(CHEMBL4279006)
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Escherichia coli PgaB expressed in Escherichia coli BL21 (DE3) cells transformed with pET28 plasmid coding for PgaB42-655 using acetoxy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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