Report error Found 168 with Last Name = 'thoreen' and Initial = 'cc'
Affinity DataIC50: 0.290nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human mTORMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of P110 alpha/p85alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of P110gammaMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of hVPS34More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of PI4K betaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of P110delta/P85alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3K-C2betaMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of PI3K-C2alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human VPS34More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 171nMAssay Description:Inhibition of P110gammaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Dana-Farber Cancer Institute
Curated by ChEMBL
Dana-Farber Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 176nMAssay Description:Inhibition of PI3K-C2 alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair