Found 304 with Last Name = 'tee' and Initial = 'dhy' TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetProtein kinase C zeta type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-zeta expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of MNK2 (unknown origin)More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of MNK2 (unknown origin)More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of MNK1 (unknown origin)More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1/2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...More data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1/2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR...More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Experimental Drug Development Centre
Curated by ChEMBL
Experimental Drug Development Centre
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of Axl (unknown origin) using 5'FAM labeled KKKKEEIYFFF-NH2 peptide as substrate incubated for 1.5 hrsMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1/2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...More data for this Ligand-Target Pair
TargetProtein kinase C iota type(Homo sapiens (Human))
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Agency For Science, Technology and Research (A*Star)
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR...More data for this Ligand-Target Pair
3D Structure (crystal)