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Found 748 with Last Name = 'dou' and Initial = 'f'
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  0.100nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM194780(7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butox...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H](+)8-OH-DPAT from human 5HT1A receptor expressed in human HeLa cells measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM194780(7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butox...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]raclopride from human D2 long receptor expressed in CHO cells measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)
Affinity DataKi:  0.400nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM194780(7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butox...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO-K1 cells measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  0.720nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423301(US10501452, Compound 7)
Affinity DataKi:  0.900nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  1nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to D3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423301(US10501452, Compound 7)
Affinity DataKi:  1.90nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423302(US10501452, Compound 8)
Affinity DataKi:  2.40nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  2.40nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423302(US10501452, Compound 8)
Affinity DataKi:  2.80nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to D2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423303(US10501452, Compound 9)
Affinity DataKi:  3.10nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423316(US10501452, Compound 22)
Affinity DataKi:  3.20nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]prazosin from rat cerebral cortex alpha1 adrenergic receptor measured after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM50556105(CHEMBL4743324)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  3.55nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423307(US10501452, Compound 13)
Affinity DataKi:  3.60nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Jiangsu Marine Resources Development Research Institute

Curated by ChEMBL
LigandPNGBDBM50509922(CHEMBL4575319)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-mepyramine from histamine H1 receptor in guinea pig cerebellum homogenates incubated for 60 mins by Cheng and Prusoff equation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423305(US10501452, Compound 11)
Affinity DataKi:  3.60nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423303(US10501452, Compound 9)
Affinity DataKi:  3.70nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]spiperone from D2 receptor in rat striatum measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423303(US10501452, Compound 9)
Affinity DataKi:  3.90nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423298(US10501452, Compound 4)
Affinity DataKi:  3.90nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423304(US10501452, Compound 10)
Affinity DataKi:  4.60nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]5-CT from rat cerebral cortex 5HT7 receptor measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423306(US10501452, Compound 12)
Affinity DataKi:  5.5nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423330(US10501452, Compound E)
Affinity DataKi:  5.60nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  5.60nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423304(US10501452, Compound 10)
Affinity DataKi:  5.80nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423322(US10501452, Compound 28)
Affinity DataKi:  5.80nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  5.90nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423316(US10501452, Compound 22)
Affinity DataKi:  6.5nMAssay Description:5-HT1A: (1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Jiangsu Marine Resources Development Research Institute

Curated by ChEMBL
LigandPNGBDBM50509934(CHEMBL4557586)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]-mepyramine from histamine H1 receptor in guinea pig cerebellum homogenates incubated for 60 mins by Cheng and Prusoff equation a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423302(US10501452, Compound 8)
Affinity DataKi:  6.70nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]spiperone from D2 receptor in rat striatum measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423308(US10501452, Compound 14)
Affinity DataKi:  6.90nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423308(US10501452, Compound 14)
Affinity DataKi:  7.20nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423322(US10501452, Compound 28)
Affinity DataKi:  7.40nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Nhwa Pharma.

US Patent
LigandPNGBDBM423318(US10501452, Compound 24)
Affinity DataKi:  7.5nMAssay Description:5-HT2A:(1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423303(US10501452, Compound 9)
Affinity DataKi:  7.90nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423325(US10501452, Compound 31)
Affinity DataKi:  8.30nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423304(US10501452, Compound 10)
Affinity DataKi:  8.40nMAssay Description:5-HT7: (1) The prepared membrane was applied with buffer, and homogenizer was used for evenly dispersing. 15 tubes were mixed into a 100 ml container...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  8.60nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM423302(US10501452, Compound 8)
Affinity DataKi:  8.70nMAssay Description:D2:Procedures(1) The prepared membrane was applied with appropriate amount of buffer, and homogenizer was used for evenly dispersing. 15 tubes were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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