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Found 55 with Last Name = 'baronissi' and Initial = 'g'
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)
Affinity DataIC50:  0.260nMAssay Description:Antagonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596184(CHEMBL5205127)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50023198(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)
Affinity DataIC50:  4.30nMAssay Description:Antagonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human CysLT2 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured af...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596187(CHEMBL5174405)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured af...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596185(CHEMBL5181326)
Affinity DataIC50:  2.10E+3nMAssay Description:Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596188(CHEMBL5169385)
Affinity DataIC50:  2.80E+3nMAssay Description:Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50023198(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human CysLT2 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596186(CHEMBL5173307)
Affinity DataIC50:  3.90E+3nMAssay Description:Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596184(CHEMBL5205127)
Affinity DataIC50: >5.00E+3nMAssay Description:Antagonist activity at human CysLT2 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596189(CHEMBL5189181)
Affinity DataIC50:  5.11E+3nMAssay Description:Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596190(CHEMBL5192002)
Affinity DataIC50:  9.63E+3nMAssay Description:Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535379(CHEMBL4445722)
Affinity DataEC50:  1.40E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535380(CHEMBL4578551)
Affinity DataEC50:  5.40E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535381(CHEMBL4591419)
Affinity DataEC50:  300nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535382(CHEMBL4588863)
Affinity DataEC50:  460nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535383(CHEMBL4436469)
Affinity DataEC50:  2.93E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM21674((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...)
Affinity DataEC50:  2.00E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535384(CHEMBL4465344)
Affinity DataEC50:  1.97E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535385(CHEMBL4455475)
Affinity DataEC50:  670nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535386(CHEMBL4535914)
Affinity DataEC50:  3.59E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535387(CHEMBL4585144)
Affinity DataEC50:  830nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596193(CHEMBL5177797)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596189(CHEMBL5189181)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596190(CHEMBL5192002)
Affinity DataEC50:  100nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50013526(2-(3-Butoxy-phenoxymethyl)-quinoline | CHEMBL18775)
Affinity DataEC50:  500nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596194(CHEMBL5173976)
Affinity DataEC50:  170nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596195(CHEMBL5172427)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596196(CHEBI:16978 | CHEMBL451509)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50297387((5S,6R,7E,9E,11Z,14Z)-6-(cystein-S-yl)-5-hydroxyic...)
Affinity DataEC50:  104nMAssay Description:Agonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596196(CHEBI:16978 | CHEMBL451509)
Affinity DataEC50:  8.90nMAssay Description:Agonist activity at human CysLT2 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human CysLT2 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteinyl leukotriene receptor 2(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50297387((5S,6R,7E,9E,11Z,14Z)-6-(cystein-S-yl)-5-hydroxyic...)
Affinity DataEC50:  293nMAssay Description:Agonist activity at human CysLT2 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50012434((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596191(CHEMBL5202995)
Affinity DataEC50:  1.65E+4nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596187(CHEMBL5174405)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50596188(CHEMBL5169385)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity against human GPBAR1 expressed in HEK293T cells assessed as transactivation of cAMP-responsive element incubated for 18 hrs by Dual-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535378(CHEMBL4562865)
Affinity DataEC50:  2.80E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535377(CHEMBL4553281)
Affinity DataEC50:  740nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM21675((4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethy...)
Affinity DataEC50:  500nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1...)
Affinity DataEC50:  20nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535376(CHEMBL4451432)
Affinity DataEC50:  1.59E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535375(CHEMBL4592387)
Affinity DataEC50:  6.67E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535374(CHEMBL4591348)
Affinity DataEC50:  2.06E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535373(CHEMBL4471591)
Affinity DataEC50:  1.02E+4nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535372(CHEMBL4532035)
Affinity DataEC50:  1.15E+3nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50535371(CHEMBL4455911)
Affinity DataEC50:  730nMAssay Description:Transactivation of human FXR (unknown origin) expressed in HepG2 cells co-expressing pSG5RXR/pGL4.70 after 24 hrs post transfection by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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