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Found 235 with Last Name = 'manchester' and Initial = 'j'
TargetToxin ParE(Escherichia coli)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047341(CHEMBL3314585)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of ATPase activity of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToxin ParE(Escherichia coli)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047314(CHEMBL3314580)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of ATPase activity of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047345(CHEMBL3314588)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470392(CHEMBL4283208)
Affinity DataIC50:  2nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470399(CHEMBL4286573)
Affinity DataIC50:  2nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388101(CHEMBL2059380)
Affinity DataIC50:  2nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470392(CHEMBL4283208)
Affinity DataIC50:  3nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470406(CHEMBL4295081)
Affinity DataIC50:  3nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470397(CHEMBL4294536)
Affinity DataIC50:  3nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470407(CHEMBL4286625)
Affinity DataIC50:  4nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470400(CHEMBL4289998)
Affinity DataIC50:  4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470403(CHEMBL4294467)
Affinity DataIC50:  4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388100(CHEMBL2059379)
Affinity DataIC50:  4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470393(CHEMBL4291061)
Affinity DataIC50:  4nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470401(CHEMBL4290062)
Affinity DataIC50:  5nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388092(CHEMBL2059196)
Affinity DataIC50:  5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470394(CHEMBL4281775)
Affinity DataIC50:  6nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50006565(CHEMBL3235085)
Affinity DataIC50:  6nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470396(CHEMBL4293447)
Affinity DataIC50:  6nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470403(CHEMBL4294467)
Affinity DataIC50:  6nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470404(CHEMBL4279382)
Affinity DataIC50:  7nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470402(CHEMBL4278317)
Affinity DataIC50:  8nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470395(CHEMBL4279313)
Affinity DataIC50:  8nMAssay Description:Displacement of 2-[125I]-Iodomelatonin from human MT1 receptor expressed in CHO cell membranes after 120 mins by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470394(CHEMBL4281775)
Affinity DataIC50:  8nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388097(CHEMBL2059375)
Affinity DataIC50:  9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B expressed in Escherichia coli BL21(DE3) cells assessed ATP hydrolysis activity after 18 to 24 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470400(CHEMBL4289998)
Affinity DataIC50:  9nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470395(CHEMBL4279313)
Affinity DataIC50:  9nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470405(CHEMBL4289650)
Affinity DataIC50:  9nMAssay Description:Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047346(CHEMBL3314589)
Affinity DataIC50: <9.80nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047347(CHEMBL3314590)
Affinity DataIC50: <9.80nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047348(CHEMBL3314591)
Affinity DataIC50: <9.80nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470405(CHEMBL4289650)
Affinity DataIC50:  10nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047330(CHEMBL3314539)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047331(CHEMBL3314540)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047334(CHEMBL3314543)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047335(CHEMBL3353959)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047336(CHEMBL3314545)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047337(CHEMBL3314546)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047338(CHEMBL3314582)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047339(CHEMBL3314583)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047340(CHEMBL3314584)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047341(CHEMBL3314585)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047343(CHEMBL3314586)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047344(CHEMBL3314587)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50006565(CHEMBL3235085)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity in Staphylococcus aureus GyrB tetramer in presence of Escherichia coli GyrA by ammonium molybdate/malachite green-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50006566(CHEMBL3235086)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity in Staphylococcus aureus GyrB tetramer in presence of Escherichia coli GyrA by ammonium molybdate/malachite green-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50006567(CHEMBL3235087)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity in Staphylococcus aureus GyrB tetramer in presence of Escherichia coli GyrA by ammonium molybdate/malachite green-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50006568(CHEMBL3235088)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity in Staphylococcus aureus GyrB tetramer in presence of Escherichia coli GyrA by ammonium molybdate/malachite green-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50006569(CHEMBL3235089)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity in Staphylococcus aureus GyrB tetramer in presence of Escherichia coli GyrA by ammonium molybdate/malachite green-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50006570(CHEMBL3235090)
Affinity DataIC50: <10nMAssay Description:Inhibition of ATPase activity in Staphylococcus aureus GyrB tetramer in presence of Escherichia coli GyrA by ammonium molybdate/malachite green-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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