TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Inhibition of pig kidney DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Sus scrofa (pig))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 56.2nMAssay Description:Inhibition of pig kidney DPP4More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.100nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.400nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.800nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1.30nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cells by Amplex Red assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of serotonin hydrochloride-induced calcium fl...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
TargetAryl hydrocarbon receptor(Danio rerio)
Gwangju Institute of Science and Technology
Curated by ChEMBL
Gwangju Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Korea Research Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 4.80nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human DGAT1 expressed in human Hep3B cells incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid sc...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells after 3 hrs by HTRF cortisol assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 5nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair