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Found 200 with Last Name = 'minguez' and Initial = 'jm'
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389083(CHEMBL2064535)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389079(CHEMBL2064532)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389081(CHEMBL2064534)
Affinity DataIC50: <5nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389081(CHEMBL2064534)
Affinity DataIC50: <5nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389087(CHEMBL2064533)
Affinity DataIC50: <5nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540172(CHEMBL4637426)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389080(CHEMBL2064515)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389086(CHEMBL2064531)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012647(CHEMBL2396989)
Affinity DataIC50:  10nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540172(CHEMBL4637426)
Affinity DataIC50:  10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389085(CHEMBL2064520)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389088(CHEMBL2064516)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389089(CHEMBL2064517)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540171(CHEMBL4643727)
Affinity DataIC50:  18nMAssay Description:Inhibition of BACE1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389082(CHEMBL2064536)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012647(CHEMBL2396989)
Affinity DataIC50:  20nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540171(CHEMBL4643727)
Affinity DataIC50:  22nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389079(CHEMBL2064532)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540171(CHEMBL4643727)
Affinity DataIC50:  28nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389085(CHEMBL2064520)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389087(CHEMBL2064533)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389082(CHEMBL2064536)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540170(CHEMBL4636286)
Affinity DataIC50:  44nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389091(CHEMBL2064519)
Affinity DataIC50:  45nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389088(CHEMBL2064516)
Affinity DataIC50:  65nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540170(CHEMBL4636286)
Affinity DataIC50:  67nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389090(CHEMBL2064518)
Affinity DataIC50:  86nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389090(CHEMBL2064518)
Affinity DataIC50:  95nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389093(CHEMBL2064522)
Affinity DataIC50:  107nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50:  129nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389089(CHEMBL2064517)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389091(CHEMBL2064519)
Affinity DataIC50:  166nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389093(CHEMBL2064522)
Affinity DataIC50:  172nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389086(CHEMBL2064531)
Affinity DataIC50:  176nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389083(CHEMBL2064535)
Affinity DataIC50:  185nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389084(CHEMBL2064538)
Affinity DataIC50:  195nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50:  233nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012632(CHEMBL2333941)
Affinity DataIC50:  239nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50012632(CHEMBL2333941)
Affinity DataIC50:  288nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389080(CHEMBL2064515)
Affinity DataIC50:  316nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389084(CHEMBL2064538)
Affinity DataIC50:  758nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM8552(2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540168(CHEMBL4644249)
Affinity DataIC50:  990nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells using mcaFRET peptide as substrate after 20 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM8548(2-(benzylsulfanyl)-5-(pyridin-4-yl)-1,3,4-oxadiazo...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540168(CHEMBL4644249)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM8548(2-(benzylsulfanyl)-5-(pyridin-4-yl)-1,3,4-oxadiazo...)
Affinity DataIC50:  2.24E+3nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389092(CHEMBL2064521)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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