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Found 151 with Last Name = 'kilgore' and Initial = 'k'
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372652(CHEMBL410029)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220087(2-(3,5-dichlorophenyl)-7-methylpyrido[2,3-d]pyrimi...)
Affinity DataIC50:  0.720nMAssay Description:Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372652(CHEMBL410029)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372636(CHEMBL429584)
Affinity DataIC50:  0.880nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215294(2-(N-(6-chloro-7-methyl-2,3-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220096(3-methoxy-5-(7-methylpyrido[2,3-d]pyrimidin-2-yl)b...)
Affinity DataIC50:  1.20nMAssay Description:Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372657(CHEMBL273054)
Affinity DataIC50:  1.54nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372633(CHEMBL270502)
Affinity DataIC50:  1.61nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215284(2-(N-(7-chloro-6-methyl-2,3-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215283(2-(N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroqui...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372647(CHEMBL272007)
Affinity DataIC50:  2.69nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372632(CHEMBL273113)
Affinity DataIC50:  3.46nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215282(CHEMBL429296 | N-(6-chloro-7-methyl-2,3-dioxo-1,2,...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372639(CHEMBL271997)
Affinity DataIC50:  4.24nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220088(3-methoxy-5-(pyrido[2,3-d]pyrimidin-2-yl)benzonitr...)
Affinity DataIC50:  4.95nMAssay Description:Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372635(CHEMBL272245)
Affinity DataIC50:  6.12nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224920(3-methoxy-5-(2-methyl-1,6-naphthyridin-7-yl)benzon...)
Affinity DataIC50:  6.19nMAssay Description:Antagonist activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372636(CHEMBL429584)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234348(4-((6-(4-methoxybenzylcarbamoyl)-4-oxopyrido[3,4-d...)
Affinity DataIC50:  6.72nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372649(CHEMBL408646)
Affinity DataIC50:  7.82nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215286(CHEMBL399275 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215286(CHEMBL399275 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372657(CHEMBL273054)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372641(CHEMBL409111)
Affinity DataIC50:  9.95nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372633(CHEMBL270502)
Affinity DataIC50:  11nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215281(CHEMBL248443 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372640(CHEMBL429596)
Affinity DataIC50:  11nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215287(CHEMBL247035 | N-(3-methoxybenzyl)-N-(6,7-dichloro...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372629(CHEMBL272246)
Affinity DataIC50:  13.5nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372643(CHEMBL429247)
Affinity DataIC50:  13.8nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372656(CHEMBL271148)
Affinity DataIC50:  13.9nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215296(CHEMBL401849 | N-(7-chloro-6-methyl-2,3-dioxo-1,2,...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372646(CHEMBL272008)
Affinity DataIC50:  16.4nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372635(CHEMBL272245)
Affinity DataIC50:  18nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372632(CHEMBL273113)
Affinity DataIC50:  18nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215285(CHEMBL400508 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372631(CHEMBL406919)
Affinity DataIC50:  19.3nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215276(CHEMBL399519 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372647(CHEMBL272007)
Affinity DataIC50:  21.2nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215281(CHEMBL248443 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215281(CHEMBL248443 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234334(BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIA...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372630(CHEMBL271535)
Affinity DataIC50:  25.3nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372641(CHEMBL409111)
Affinity DataIC50:  28nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234348(4-((6-(4-methoxybenzylcarbamoyl)-4-oxopyrido[3,4-d...)
Affinity DataIC50:  30.5nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372637(CHEMBL272261)
Affinity DataIC50:  31.1nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372655(CHEMBL407090)
Affinity DataIC50:  36.3nMAssay Description:Inhibition of human MMP13 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50372639(CHEMBL271997)
Affinity DataIC50:  37nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220085(2-(3-bromophenyl)-7-methylpyrido[2,3-d]pyrimidine ...)
Affinity DataIC50:  38nMAssay Description:Antagonistic activity at rat mGluR5 expressed in CHO cells assessed as inhibition of quisqualate stimulated calcium mobilization by FLIPR technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215279(CHEMBL248439 | N-(6,7-dichloro-2,3-dioxo-1,2,3,4-t...)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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