Affinity DataKi: 323nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.20E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at P2X7 receptor in human LPS-stimulated monocytes assessed as inhibition of ATP-induced IL-1beta release by ELISA in presence of...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at P2X7 receptor in human LPS-stimulated monocytes assessed as inhibition of ATP-induced IL1-beta release by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced YOPRO-1 uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]rolipram from mouse brain homogenatesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at P2X7 receptor expressed in HEK293 cells assessed as inhibition of ATP-induced YOPRO-1 uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at P2X7 receptor in human LPS-stimulated monocytes assessed as inhibition of ATP-induced IL1-beta release by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Antagonist activity at P2X7 receptor in human LPS-stimulated monocytes assessed as inhibition of ATP-induced IL1-beta release by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibitory activity on human eosinophil phosphodiesterase 4.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair