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Found 222 with Last Name = 'chen' and Initial = 'lw'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123932(CHEMBL3622226)
Affinity DataIC50:  209nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123932(CHEMBL3622226)
Affinity DataIC50:  210nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134262(CHEMBL3746557)
Affinity DataIC50:  260nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134262(CHEMBL3746557)
Affinity DataIC50:  260nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  280nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50075033(CHEMBL3410356)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  410nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50075032(CHEMBL3410355)
Affinity DataIC50:  460nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134262(CHEMBL3746557)
Affinity DataIC50:  510nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  540nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134236(CHEMBL3746473)
Affinity DataIC50:  600nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134236(CHEMBL3746473)
Affinity DataIC50:  601nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123934(CHEMBL3622785)
Affinity DataIC50:  794nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123934(CHEMBL3622785)
Affinity DataIC50:  810nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase(Staphylococcus aureus (strain MSSA476))
Nanjing University

LigandPNGBDBM199134(2-(2-Methyl-5-nitro-1H-imidazol-1-yl)-ethyl-5-(4-m...)
Affinity DataIC50:  920nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50075035(CHEMBL3410357)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50074899(CHEMBL3410343)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134258(CHEMBL3746711)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50075039(CHEMBL3410361)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124122(CHEMBL3622800)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134258(CHEMBL3746711)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134241(CHEMBL3746642)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134241(CHEMBL3746642)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase(Staphylococcus aureus (strain MSSA476))
Nanjing University

LigandPNGBDBM199139(2-(2-Methyl-5-nitro-1H-imidazol-1-yl)-ethyl-1-(4-c...)
Affinity DataIC50:  1.67E+3nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50074909(CHEMBL3410351)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123932(CHEMBL3622226)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP9 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134236(CHEMBL3746473)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123984(CHEMBL3622791)
Affinity DataIC50:  2.15E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123984(CHEMBL3622791)
Affinity DataIC50:  2.15E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50074891(CHEMBL3410341)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50075037(CHEMBL3410359)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50074888(CHEMBL3410340)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124122(CHEMBL3622800)
Affinity DataIC50:  2.52E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP9 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50074892(CHEMBL3410342)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123979(CHEMBL3622786)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123979(CHEMBL3622786)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50075041(CHEMBL3410363)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134258(CHEMBL3746711)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124100(CHEMBL3622795)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124100(CHEMBL3622795)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124124(CHEMBL3622220)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124124(CHEMBL3622220)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50123934(CHEMBL3622785)
Affinity DataIC50:  3.19E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP9 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124126(CHEMBL3622221)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50124126(CHEMBL3622221)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50074885(CHEMBL3410339)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134264(CHEMBL3746212)
Affinity DataIC50:  3.45E+3nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50074907(CHEMBL3410349)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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