TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 209nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 601nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 794nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+3nMpH: 7.9Assay Description:The assays were conducted at 37 °C in a mixture containing 100 mM Tris/Cl pH 7.9, 50 mM KCl, 16 mM MgCl2, 5 mM ATP, 3 mM DTT, 4 mg/ml E. coli MRE600 ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP9 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP9 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP9 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of APMA-activated human recombinant MMP2 incubated for 5 mins using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Nanjing Medical University
Curated by ChEMBL
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of human recombinant COX2 by ELISAMore data for this Ligand-Target Pair