Affinity DataKi: 1.60nMAssay Description:Inhibition of aromatase in human placental microsomesMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Agonist activity at GPER (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of aromatase in rat mammary tumorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cells assessed as inhibition of [3H]estrone and [3H]estradiol formation using [3H]estrone sulfate as su...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of aromatase in human breast tumorMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of aromatase in human breast tumorMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of STS in human placental microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of aromatase in human breast tumorMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of aromatase in human breast tumorMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Displacement of EL red from human full-length ER-beta expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Displacement of EL red from human full-length ER-beta expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Displacement of EL red from human full-length ER-alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 267nMAssay Description:Displacement of EL red from human full-length ER-beta by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+3nMAssay Description:Displacement of EL red from human full-length ER-beta expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 4.74E+3nMAssay Description:Displacement of EL red from human full-length ER-alpha expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization as...More data for this Ligand-Target Pair
Affinity DataIC50: 5.57E+3nMAssay Description:Displacement of EL red from human full-length ER-beta expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 5.88E+3nMAssay Description:Displacement of EL red from human full-length ER-alpha expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of aromatase in human breast tumorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+4nMAssay Description:Displacement of EL red from human full-length ER-alpha expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+6nMAssay Description:Displacement of EL red from human full-length ER-alpha expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization as...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0140nMAssay Description:Modulation of ER-alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.660nMAssay Description:Agonist activity at human ER-beta transfected in HEC-1 cells assessed as transcriptional activation incubated for 24 hrs by dual luciferase reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Modulation of ER-beta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at human ER-beta ligand binding domain transfected in African green monkey COS-7 cells incubated for overnight by Dual-Glo luciferas...More data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Agonist activity at human ER-alpha ligand binding domain transfected in African green monkey COS-7 cells incubated for overnight by Dual-Glo lucifera...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at human ER-alpha transfected in African green monkey COS-7 cells measured after 24 hrs by Steady-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at human ER-alpha transfected in African green monkey COS-7 cells measured after 24 hrs by Steady-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human ER-beta transfected in African green monkey COS-7 cells measured after 24 hrs by Steady-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human ER-beta transfected in African green monkey COS-7 cells measured after 24 hrs by Steady-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Agonist activity at ER-beta (unknown origin)More data for this Ligand-Target Pair