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Found 350 with Last Name = 'genicot' and Initial = 'mj'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245811((1S,2R)-1-(2-ethylphenoxy)-2-((methylamino)methyl)...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245962((1S,2R)-1-(2,4-dimethylphenoxy)-2-((methylamino)me...)
Affinity DataIC50:  2nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245863((1S,2R)-2-((methylamino)methyl)-1-(2-(methylthio)p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272654(CHEMBL526270 | N-methyl((3S,4S)-4-(2-(trifluoromet...)
Affinity DataIC50:  3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245963((1S,2R)-1-(3-fluoro-2-methylphenoxy)-2-((methylami...)
Affinity DataIC50:  3nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272655(((3S,4S)-4-(3-fluoro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50370475(S,S-REBOXETINE)
Affinity DataIC50:  3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245961((1S,2R)-1-(2,3-dimethylphenoxy)-2-((methylamino)me...)
Affinity DataIC50:  3nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246491((1S,2R)-2-((methylamino)methyl)-1-(2-(naphthalen-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246494((1S,2R)-2-((methylamino)methyl)-1-(o-tolyloxy)-2,3...)
Affinity DataIC50:  3nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246014((1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylam...)
Affinity DataIC50:  4nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272730(((3S,4S)-4-(2-fluoro-6-(trifluoromethyl)phenoxy)-3...)
Affinity DataIC50:  4nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272728(((3S,4S)-4-(2-fluoro-6-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272730(((3S,4S)-4-(2-fluoro-6-(trifluoromethyl)phenoxy)-3...)
Affinity DataIC50:  4nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246013((1S,2R)-1-(3-hydroxy-2-methylphenoxy)-2-((methylam...)
Affinity DataIC50:  4nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246012((1S,2R)-1-(2-fluoro-6-methylphenoxy)-2-((methylami...)
Affinity DataIC50:  5nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245964((1S,2R)-1-(4-fluoro-2-methylphenoxy)-2-((methylami...)
Affinity DataIC50:  5nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50022784((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...)
Affinity DataIC50:  5nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245810((1S,2R)-1-(2-chlorophenoxy)-2-((methylamino)methyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50022784((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...)
Affinity DataIC50:  5nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272717(CHEMBL505433 | N-methyl((3S,4S)-4-(o-tolyloxy)-3,4...)
Affinity DataIC50:  5nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)
Affinity DataIC50:  5nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245962((1S,2R)-1-(2,4-dimethylphenoxy)-2-((methylamino)me...)
Affinity DataIC50:  5nMAssay Description:Inhibition of serotonin uptake at human SERT transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245964((1S,2R)-1-(4-fluoro-2-methylphenoxy)-2-((methylami...)
Affinity DataIC50:  6nMAssay Description:Inhibition of serotonin uptake at human SERT transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272654(CHEMBL526270 | N-methyl((3S,4S)-4-(2-(trifluoromet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272745(((3R,4R)-4-(2-ethylphenoxy)-3,4-dihydro-2H-chromen...)
Affinity DataIC50:  7nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272728(((3S,4S)-4-(2-fluoro-6-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272646(CHEMBL525375 | N-methyl((1R,2S)-1-(o-tolyloxy)-1,2...)
Affinity DataIC50:  7nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246492(CHEMBL455447 | N-methyl((1R,2S)-1-(o-tolyloxy)-2,3...)
Affinity DataIC50:  7nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245965((1S,2R)-1-(5-fluoro-2-methylphenoxy)-2-((methylami...)
Affinity DataIC50:  7nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272691(((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-1H-isochr...)
Affinity DataIC50:  8nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272729(((3S,4S)-4-(2-ethyl-6-fluorophenoxy)-3,4-dihydro-1...)
Affinity DataIC50:  8nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272655(((3S,4S)-4-(3-fluoro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272749(3-methyl-4-((3S,4S)-3-((methylamino)methyl)-3,4-di...)
Affinity DataIC50:  8nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272725(((3S,4S)-4-(3-chloro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246492(CHEMBL455447 | N-methyl((1R,2S)-1-(o-tolyloxy)-2,3...)
Affinity DataIC50:  10nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246548(CHEMBL462402 | rac-2-((methylamino)methyl)-1-(o-to...)
Affinity DataIC50:  10nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246491((1S,2R)-2-((methylamino)methyl)-1-(2-(naphthalen-1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of serotonin uptake at human SERT transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245809((1S,2R)-1-(2-fluorophenoxy)-2-((methylamino)methyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272727(((3S,4S)-4-(5-fluoro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272726(((3S,4S)-4-(4-fluoro-2-methylphenoxy)-3,4-dihydro-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272653(CHEMBL497493 | N-methyl((3S,4S)-4-(2-(methylthio)p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50246014((1S,2R)-1-(4-hydroxy-2-methylphenoxy)-2-((methylam...)
Affinity DataIC50:  14nMAssay Description:Inhibition of serotonin uptake at human SERT transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)
Affinity DataIC50:  15nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272722(((3S,4S)-4-(2-ethylphenoxy)-3,4-dihydro-1H-isochro...)
Affinity DataIC50:  15nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272691(((3S,4S)-4-(2-chlorophenoxy)-3,4-dihydro-1H-isochr...)
Affinity DataIC50:  17nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245812((1S,2R)-1-(2-methoxyphenoxy)-2-((methylamino)methy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272717(CHEMBL505433 | N-methyl((3S,4S)-4-(o-tolyloxy)-3,4...)
Affinity DataIC50:  18nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272645(CHEMBL445082 | N-methyl((3R,4R)-4-(o-tolyloxy)-3,4...)
Affinity DataIC50:  26nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272643(((3R,4R)-4-(2-chlorophenoxy)-3,4-dihydro-2H-chrome...)
Affinity DataIC50:  26nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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