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Found 74 with Last Name = 'pflum' and Initial = 'mkh'
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC3 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464530(CHEMBL4287851)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  31nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC1 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC1 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464530(CHEMBL4287851)
Affinity DataIC50:  48nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464529(CHEMBL4284448)
Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464527(CHEMBL4285869)
Affinity DataIC50:  74nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50:  79nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464527(CHEMBL4285869)
Affinity DataIC50:  88nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464528(CHEMBL4283418)
Affinity DataIC50:  95nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  96nMAssay Description:Inhibition of HDAC2 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  96nMAssay Description:Inhibition of HDAC2 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464532(CHEMBL4295105)
Affinity DataIC50:  110nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464529(CHEMBL4284448)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464528(CHEMBL4283418)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50:  160nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimet...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268604(CHEMBL4102833)
Affinity DataIC50:  270nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464532(CHEMBL4295105)
Affinity DataIC50:  290nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268605(CHEMBL4086409)
Affinity DataIC50:  320nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268604(CHEMBL4102833)
Affinity DataIC50:  380nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268603(CHEMBL4064944)
Affinity DataIC50:  410nMAssay Description:Inhibition of HDAC6 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268603(CHEMBL4064944)
Affinity DataIC50:  420nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268605(CHEMBL4086409)
Affinity DataIC50:  430nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  540nMAssay Description:Inhibition of HDAC8 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268605(CHEMBL4086409)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268605(CHEMBL4086409)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268605(CHEMBL4086409)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268603(CHEMBL4064944)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268603(CHEMBL4064944)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of HDAC1 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268604(CHEMBL4102833)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HDAC3 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268603(CHEMBL4064944)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464533(CHEMBL4277569)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of HDAC in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268604(CHEMBL4102833)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of HDAC2 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of HDAC1 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of HDAC2 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50268604(CHEMBL4102833)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) by ELISA-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464531(CHEMBL4288220)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of HDAC3 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50434126(CHEMBL2381517)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of HDAC in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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